8FKE
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR32904
Summary for 8FKE
Entry DOI | 10.2210/pdb8fke/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, Nuclear receptor corepressor 1, 2-chloro-N-(2-methylpyridin-4-yl)-5-nitrobenzamide, ... (5 entities in total) |
Functional Keywords | nuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-agonist complex |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 34431.22 |
Authors | |
Primary citation | MacTavish, B.S.,Kojetin, D.J. Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR32904 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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