8FH7
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-003
Summary for 8FH7
Entry DOI | 10.2210/pdb8fh7/pdb |
Descriptor | Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {7-[(5-chloro-1,3-benzothiazol-2-yl)methyl]-8-oxo-7,8-dihydropyrazino[2,3-d]pyridazin-5-yl}acetic acid, ... (5 entities in total) |
Functional Keywords | inhibitor complex, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37231.75 |
Authors | |
Primary citation | Arenas, R.,Wilson, D.K. Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-003 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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