8FFX
Crystal structure of HIV-1 reverse transcriptase in complex with non-nucleoside inhibitor 19980
Summary for 8FFX
Entry DOI | 10.2210/pdb8ffx/pdb |
Descriptor | Reverse transcriptase/ribonuclease H, p51 RT, DIMETHYL SULFOXIDE, ... (7 entities in total) |
Functional Keywords | non nucleotide-reverse transcriptase inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Human immunodeficiency virus type 1 BH10 More |
Total number of polymer chains | 2 |
Total formula weight | 114835.54 |
Authors | Rumrill, S.R.,Ruiz, F.X.,Arnold, E. (deposition date: 2022-12-10, release date: 2023-04-26, Last modification date: 2024-05-22) |
Primary citation | Mansouri, M.,Rumrill, S.,Dawson, S.,Johnson, A.,Pinson, J.A.,Gunzburg, M.J.,Latham, C.F.,Barlow, N.,Mbogo, G.W.,Ellenberg, P.,Headey, S.J.,Sluis-Cremer, N.,Tyssen, D.,Bauman, J.D.,Ruiz, F.X.,Arnold, E.,Chalmers, D.K.,Tachedjian, G. Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach. Molecules, 28:-, 2023 Cited by PubMed: 37049868DOI: 10.3390/molecules28073103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
Download full validation report