8DZH

Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody MB.02

Summary for 8DZH

• Entry DOI: 10.2210/pdb8dzh/pdb
• EMDB information: 27798 27799 27800
• Descriptor: Spike glycoprotein, antibody MB.02 heavy chain, antibody MB.02 light chain, ... (5 entities in total)
• Functional Keywords: viral protein, human antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 9
• Total formula weight: 517386.71

Authors

Hu, Y.,Xiong, Y. (deposition date: 2022-08-07, release date: 2022-08-31, Last modification date: 2024-10-30)

• Primary citation: Ren, P.,Hu, Y.,Peng, L.,Yang, L.,Suzuki, K.,Fang, Z.,Bai, M.,Zhou, L.,Feng, Y.,Zou, Y.,Xiong, Y.,Chen, S.; Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.; Signal Transduct Target Ther, 8:281-281, 2023; PubMed: 37518189; DOI: 10.1038/s41392-023-01509-1

Experimental method

ELECTRON MICROSCOPY (3.2 Å)