8DV6

Zika virus envelope protein structure in complex with a potent Human mAb

This is a non-PDB format compatible entry.

Summary for 8DV6

• Entry DOI: 10.2210/pdb8dv6/pdb
• Descriptor: Envelope protein E, mAb Fab Heavy Chain, mAb Fab Light Chain (3 entities in total)
• Functional Keywords: zika virus, envelope protein, neutralizing antibody, neutralization mechanism, flavivirus, viral protein, viral protein-immune system complex
• Biological source: Zika virus ZIKV/Human/Cambodia/FSS13025/2010 (ZIKV); More
• Total number of polymer chains: 6
• Total formula weight: 188458.73

Authors

Cameron, A.,Puhl, A.C.,deSilva, A.M.,Premkumar, L. (deposition date: 2022-07-28, release date: 2023-01-04, Last modification date: 2023-10-25)

• Primary citation: Adams, C.,Carbaugh, D.L.,Shu, B.,Ng, T.S.,Castillo, I.N.,Bhowmik, R.,Segovia-Chumbez, B.,Puhl, A.C.,Graham, S.,Diehl, S.A.,Lazear, H.M.,Lok, S.M.,de Silva, A.M.,Premkumar, L.; Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.; Plos Pathog., 19:e1010814-e1010814, 2023; PubMed: 36626401; DOI: 10.1371/journal.ppat.1010814

Experimental method

X-RAY DIFFRACTION (3.38 Å)