8DRB
Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with 3-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide
Summary for 8DRB
Entry DOI | 10.2210/pdb8drb/pdb |
Descriptor | Carbonic anhydrase, 3-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide, ZINC ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase, neisseria gonorrhoeae, acetazolamide, lyase |
Biological source | Neisseria gonorrhoeae |
Total number of polymer chains | 4 |
Total formula weight | 111926.77 |
Authors | Marapaka, A.K.,Das, C.,Flaherty, D.P.,Yadav, R. (deposition date: 2022-07-20, release date: 2022-12-14, Last modification date: 2023-10-25) |
Primary citation | Marapaka, A.K.,Nocentini, A.,Youse, M.S.,An, W.,Holly, K.J.,Das, C.,Yadav, R.,Seleem, M.N.,Supuran, C.T.,Flaherty, D.P. Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase. Acs Med.Chem.Lett., 14:103-109, 2023 Cited by PubMed: 36655133DOI: 10.1021/acsmedchemlett.2c00471 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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