8DJ7
The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant
Summary for 8DJ7
Entry DOI | 10.2210/pdb8dj7/pdb |
Descriptor | Ig gamma-1 Fc chain, High affinity immunoglobulin gamma Fc receptor I, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | high affinity igg1 fc receptor, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 83880.19 |
Authors | |
Primary citation | Lu, J.,Spencer, M.,Zou, Z.,Traver, M.,Brzostowski, J.,Sun, P.D. Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release. Front Immunol, 14:1100499-1100499, 2023 Cited by PubMed: 36814926DOI: 10.3389/fimmu.2023.1100499 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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