8D52
Parathyroid hormone 1 receptor extracellular domain complexed with a peptide ligand containing (2-naphthyl)-beta-3-homoalanine
Summary for 8D52
Entry DOI | 10.2210/pdb8d52/pdb |
Descriptor | Parathyroid hormone/parathyroid hormone-related peptide receptor, PTHrP[1-36], 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | parathyroid hormone 1 receptor, signaling, beta-amino acid, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 14956.44 |
Authors | Yu, Z.,Kreitler, D.F.,Gellman, S.H. (deposition date: 2022-06-03, release date: 2023-06-14, Last modification date: 2023-12-27) |
Primary citation | Yu, Z.,Kreitler, D.F.,Chiu, Y.T.T.,Xu, R.,Bruchs, A.T.,Bingman, C.A.,Gellman, S.H. Harnessing Aromatic-Histidine Interactions through Synergistic Backbone Extension and Side Chain Modification. Angew.Chem.Int.Ed.Engl., 62:e202308100-e202308100, 2023 Cited by PubMed: 37587780DOI: 10.1002/anie.202308100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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