8D11
Crystal Structure of EcDsbA in a complex with 1-methyl-1H-pyrazol-5-amine
Summary for 8D11
Entry DOI | 10.2210/pdb8d11/pdb |
Descriptor | Thiol:disulfide interchange protein DsbA, 1-methyl-1H-pyrazol-5-amine, COPPER (II) ION, ... (4 entities in total) |
Functional Keywords | disulfide oxidoreductase, redox protein, microfrag screening, fbdd, fragment, antimicrobial protein, oxidoreductase |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 2 |
Total formula weight | 43053.42 |
Authors | Whitehouse, R.L.,Ilyichova, O.V.,Taylor, A.J. (deposition date: 2022-05-26, release date: 2022-12-07, Last modification date: 2023-10-25) |
Primary citation | Whitehouse, R.L.,Alwan, W.S.,Ilyichova, O.V.,Taylor, A.J.,Chandrashekaran, I.R.,Mohanty, B.,Doak, B.C.,Scanlon, M.J. Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores. Rsc Med Chem, 14:135-143, 2023 Cited by PubMed: 36760747DOI: 10.1039/d2md00253a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report