8COU
Pa.FabF-C164Q in complex with 3-acetamido-4-methoxybenzoic acid
Summary for 8COU
Entry DOI | 10.2210/pdb8cou/pdb |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, FORMIC ACID, ... (6 entities in total) |
Functional Keywords | inhibitor, transferase, fabf, complex, pseudomonas aeruginosa |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 89967.48 |
Authors | |
Primary citation | Georgiou, C.,Espeland, L.O.,Bukya, H.,Yadrykhinsky, V.,Haug, B.E.,Mainkar, P.,Brenk, R. New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023 Cited by DOI: 10.26434/chemrxiv-2023-cwk25PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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