8CN4
Pa.FabF-C164Q in complex with 5-acetamido-2-chlorobenzoic acid
Summary for 8CN4
Entry DOI | 10.2210/pdb8cn4/pdb |
Related | 8CN2 |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2, GLYCEROL, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | inhibitor, transferase, fabf, complex |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 87522.38 |
Authors | |
Primary citation | Georgiou, C.,Espeland, L.O.,Bukya, H.,Yadrykhinsky, V.,Haug, B.E.,Mainkar, P.,Brenk, R. New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023 Cited by DOI: 10.26434/chemrxiv-2023-cwk25PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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