8CM8
Galectin-8 N-terminal carbohydrate recognition domain in complex with 4-(bromophenyl)phthalazinone D-galactal ligand
Summary for 8CM8
Entry DOI | 10.2210/pdb8cm8/pdb |
Descriptor | Galectin-8, 4-(4-bromophenyl)-2-[[(2~{R},3~{R},4~{R})-2-(hydroxymethyl)-3-oxidanyl-3,4-dihydro-2~{H}-pyran-4-yl]oxymethyl]phthalazin-1-one, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | galectin, phthalazinone, inhibitor, sugar binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 72662.14 |
Authors | Van Klaveren, S.,Hakansson, M.,Diehl, C.,Nilsson, N.J. (deposition date: 2023-02-17, release date: 2024-02-28) |
Primary citation | Van Klaveren, S.,Nilsson, N.J. Halogenated Galactal-Phenylphthalazinone Hybrids as Highly Selective Galectin-8N Ligands To Be Published, |
Experimental method |
Structure validation
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