8CKL
Semaphorin-5A TSR 3-4 domains in complex with sucrose octasulfate (SOS)
Summary for 8CKL
Entry DOI | 10.2210/pdb8ckl/pdb |
Related | 8CKG 8CKK 8CKM |
Related PRD ID | PRD_900013 |
Descriptor | Semaphorin-5A, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose-(1-2)-1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose, alpha-D-mannopyranose (3 entities in total) |
Functional Keywords | semaphorin, cell signalling, axon guidance cue, glycosaminoglycan binding protein, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 29812.83 |
Authors | Nagy, G.N.,Duman, R.,Harlos, K.,El Omari, K.,Wagner, A.,Jones, E.Y. (deposition date: 2023-02-15, release date: 2024-02-28, Last modification date: 2024-09-11) |
Primary citation | Nagy, G.N.,Zhao, X.F.,Karlsson, R.,Wang, K.,Duman, R.,Harlos, K.,El Omari, K.,Wagner, A.,Clausen, H.,Miller, R.L.,Giger, R.J.,Jones, E.Y. Structure and function of Semaphorin-5A glycosaminoglycan interactions. Nat Commun, 15:2723-2723, 2024 Cited by PubMed: 38548715DOI: 10.1038/s41467-024-46725-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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