8BX3
fragment-linked stabilizer for ERa - 14-3-3 interaction (1074372)
Summary for 8BX3
Entry DOI | 10.2210/pdb8bx3/pdb |
Descriptor | 14-3-3 protein sigma, ERalpha peptide, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | 14-3-3, era, fragment linking, stabilization, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 27687.80 |
Authors | Visser, E.J.,Vandenboorn, E.M.F.,Ottmann, C. (deposition date: 2022-12-07, release date: 2023-08-02, Last modification date: 2023-09-13) |
Primary citation | Visser, E.J.,Jaishankar, P.,Sijbesma, E.,Pennings, M.A.M.,Vandenboorn, E.M.F.,Guillory, X.,Neitz, R.J.,Morrow, J.,Dutta, S.,Renslo, A.R.,Brunsveld, L.,Arkin, M.R.,Ottmann, C. From Tethered to Freestanding Stabilizers of 14-3-3 Protein-Protein Interactions through Fragment Linking. Angew.Chem.Int.Ed.Engl., 62:e202308004-e202308004, 2023 Cited by PubMed: 37455289DOI: 10.1002/anie.202308004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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