8BWE
Small molecule stabilizer for 14-3-3/ChREBP (Cmd 43)
Summary for 8BWE
Entry DOI | 10.2210/pdb8bwe/pdb |
Descriptor | 14-3-3 protein sigma, Carbohydrate-responsive element-binding protein, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | 14-3-3, chrebp, stabilization, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 29388.85 |
Authors | |
Primary citation | Katz, L.S.,Visser, E.J.,Plitzko, K.F.,Pennings, M.,Cossar, P.J.,Tse, I.L.,Kaiser, M.,Brunsveld, L.,Scott, D.K.,Ottmann, C. Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity. Biorxiv, 2024 Cited by PubMed: 38405965DOI: 10.1101/2024.02.16.580675 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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