8B9R
Molecular structure of Cu(II)-bound amyloid-beta monomer implicated in inhibition of peptide self-assembly in Alzheimer's disease
Summary for 8B9R
| Entry DOI | 10.2210/pdb8b9r/pdb |
| NMR Information | BMRB: 34763 |
| Descriptor | Amyloid-beta A4 protein, COPPER (II) ION (2 entities in total) |
| Functional Keywords | amyloid-beta peptide, alzheimer's disease, copper ion, paramagnetic nmr, aggregation kinetics, metal binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 4399.40 |
| Authors | Abelein, A.,Ciofi-Baffoni, S.,Morman, C.,Kumar, R.,Giachetti, A.,Piccioli, M.,Biverstal, H. (deposition date: 2022-10-06, release date: 2023-02-01) |
| Primary citation | Abelein, A.,Ciofi-Baffoni, S.,Morman, C.,Kumar, R.,Giachetti, A.,Piccioli, M.,Biverstal, H. Molecular Structure of Cu(II)-Bound Amyloid-beta Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease. Jacs Au, 2:2571-2584, 2022 Cited by PubMed: 36465548DOI: 10.1021/jacsau.2c00438 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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