8A0M
Capsular polysaccharide synthesis multienzyme in complex with capsular polymer fragment
Summary for 8A0M
Entry DOI | 10.2210/pdb8a0m/pdb |
Descriptor | Bcs3, MAGNESIUM ION, beta-D-ribosyl-(1->1)-D-ribitol-5-phosphate, ... (4 entities in total) |
Functional Keywords | bacterial capsule synthesis, biosynthetic protein |
Biological source | Haemophilus influenzae |
Total number of polymer chains | 4 |
Total formula weight | 554609.54 |
Authors | Cifuente, J.O.,Schulze, J.,Bethe, A.,Di Domenico, V.,Litschko, C.,Budde, I.,Eidenberger, L.,Thiesler, H.,Ramon-Roth, I.,Berger, M.,Claus, H.,DAngelo, C.,Marina, A.,Gerardy-Schahn, R.,Schubert, M.,Guerin, M.E.,Fiebig, T. (deposition date: 2022-05-29, release date: 2023-04-26, Last modification date: 2024-05-01) |
Primary citation | Cifuente, J.O.,Schulze, J.,Bethe, A.,Di Domenico, V.,Litschko, C.,Budde, I.,Eidenberger, L.,Thiesler, H.,Ramon Roth, I.,Berger, M.,Claus, H.,D'Angelo, C.,Marina, A.,Gerardy-Schahn, R.,Schubert, M.,Guerin, M.E.,Fiebig, T. A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule. Nat.Chem.Biol., 19:865-877, 2023 Cited by PubMed: 37277468DOI: 10.1038/s41589-023-01324-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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