7ZP7
Crystal structure of evolved photoenzyme EnT1.3 (truncated) with bound product
Summary for 7ZP7
Entry DOI | 10.2210/pdb7zp7/pdb |
Descriptor | EnT1.3 C, (1~{R},10~{R},12~{S})-15-oxa-8-azatetracyclo[8.5.0.0^{1,12}.0^{2,7}]pentadeca-2(7),3,5-trien-9-one, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | designed photoenzyme, [2+2]-cyclase, genetic code expansion, engineered enzyme, biosynthetic protein |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 73961.60 |
Authors | Hardy, F.J.,Levy, C. (deposition date: 2022-04-26, release date: 2022-09-28, Last modification date: 2024-01-31) |
Primary citation | Trimble, J.S.,Crawshaw, R.,Hardy, F.J.,Levy, C.W.,Brown, M.J.B.,Fuerst, D.E.,Heyes, D.J.,Obexer, R.,Green, A.P. A designed photoenzyme for enantioselective [2+2] cycloadditions. Nature, 611:709-714, 2022 Cited by PubMed: 36130727DOI: 10.1038/s41586-022-05335-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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