7ZML
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G1-001
Summary for 7ZML
Entry DOI | 10.2210/pdb7zml/pdb |
Descriptor | ATP-dependent DNA helicase Q5, Gluebody G1-001, ZINC ION, ... (5 entities in total) |
Functional Keywords | helicase, apo form, nanobody complex, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 256185.65 |
Authors | Ye, M.,Makola, M.,Newman, J.A.,Fairhead, M.,MacLean, E.,Krojer, T.,Aitkenhead, H.,Bountra, C.,Gileadi, O.,von Delft, F. (deposition date: 2022-04-19, release date: 2022-06-22, Last modification date: 2024-01-31) |
Primary citation | Ye, M.,Makola, M.,Newman, J.A.,Fairhead, M.,MacLean, E.,Krojer, T.,Wright, N.D.,Koekemoer, L.,Thompson, A.,Bezerra, G.A.,Yi, G.,Li, H.,Rangel, V.L.,Mamalis, D.,Aitkenhead, H.,Gilbert, R.J.C.,Duerr, K.,Davis, B.G.,Bountra, C.,Gileadi, O.,von Delft, F. Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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