7ZML

Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G1-001

7ZML の概要

• エントリーDOI: 10.2210/pdb7zml/pdb
• 分子名称: ATP-dependent DNA helicase Q5, Gluebody G1-001, ZINC ION, ... (5 entities in total)
• 機能のキーワード: helicase, apo form, nanobody complex, hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 256185.65

構造登録者

Ye, M.,Makola, M.,Newman, J.A.,Fairhead, M.,MacLean, E.,Krojer, T.,Aitkenhead, H.,Bountra, C.,Gileadi, O.,von Delft, F. (登録日: 2022-04-19, 公開日: 2022-06-22, 最終更新日: 2024-01-31)

• 主引用文献: Ye, M.,Makola, M.,Newman, J.A.,Fairhead, M.,MacLean, E.,Krojer, T.,Wright, N.D.,Koekemoer, L.,Thompson, A.,Bezerra, G.A.,Yi, G.,Li, H.,Rangel, V.L.,Mamalis, D.,Aitkenhead, H.,Gilbert, R.J.C.,Duerr, K.,Davis, B.G.,Bountra, C.,Gileadi, O.,von Delft, F.; Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts; To Be Published,

実験手法

X-RAY DIFFRACTION (2.79 Å)