7ZLJ
Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and acceptor peptide, bound to CMT2-Fab and anti-Fab nanobody
Summary for 7ZLJ
Entry DOI | 10.2210/pdb7zlj/pdb |
EMDB information | 14782 |
Descriptor | CMT2-Fab heavy chain, Anti-Fab nanobody, CMT2-Fab light chain, ... (7 entities in total) |
Functional Keywords | c-mannosyltransferase, membrane protein |
Biological source | synthetic construct More |
Total number of polymer chains | 5 |
Total formula weight | 143945.38 |
Authors | Bloch, J.S.,Mao, R.,Mukherjee, S.,Boilevin, J.,Irobalieva, R.,Darbre, T.,Reymond, J.L.,Kossiakoff, A.A.,Goddard-Borger, E.D.,Locher, K.P. (deposition date: 2022-04-15, release date: 2023-01-11, Last modification date: 2024-10-16) |
Primary citation | Bloch, J.S.,John, A.,Mao, R.,Mukherjee, S.,Boilevin, J.,Irobalieva, R.N.,Darbre, T.,Scott, N.E.,Reymond, J.L.,Kossiakoff, A.A.,Goddard-Borger, E.D.,Locher, K.P. Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nat.Chem.Biol., 19:575-584, 2023 Cited by PubMed: 36604564DOI: 10.1038/s41589-022-01219-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.63 Å) |
Structure validation
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