7ZL7
Human GABARAP in complex with stapled peptide Pen8-ortho
Summary for 7ZL7
| Entry DOI | 10.2210/pdb7zl7/pdb |
| Descriptor | Gamma-aminobutyric acid receptor-associated protein, Pen8-ortho, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | autophagy-related protein, stapled peptide, gabarap, inhibitor, protein binding |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 31710.75 |
| Authors | Ueffing, A.,Brown, H.,Willbold, D.,Kritzer, J.A.,Weiergraeber, O.H. (deposition date: 2022-04-14, release date: 2022-08-31, Last modification date: 2024-01-31) |
| Primary citation | Brown, H.,Chung, M.,Uffing, A.,Batistatou, N.,Tsang, T.,Doskocil, S.,Mao, W.,Willbold, D.,Bast Jr., R.C.,Lu, Z.,Weiergraber, O.H.,Kritzer, J.A. Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy. J.Am.Chem.Soc., 144:14687-14697, 2022 Cited by PubMed: 35917476DOI: 10.1021/jacs.2c04699 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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