7ZKU
Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-2'dGMP)
Summary for 7ZKU
Entry DOI | 10.2210/pdb7zku/pdb |
Descriptor | Stimulator of interferon protein, 9-[(1~{S},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R})-8-(6-aminopurin-9-yl)-9-fluoranyl-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]-2-azanyl-3~{H}-purin-6-one (3 entities in total) |
Functional Keywords | sting, antiviral, activator, antiviral protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 47036.56 |
Authors | |
Primary citation | Klima, M.,Smola, M.,Boura, E. Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-2'd To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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