7ZK6
ABCB1 L335C mutant (mABCB1) in the outward facing state bound to 2 molecules of AAC
Summary for 7ZK6
| Entry DOI | 10.2210/pdb7zk6/pdb |
| EMDB information | 14756 |
| Descriptor | ATP-dependent translocase ABCB1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | abc transporter, membrane protein |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 148800.98 |
| Authors | Parey, K.,Januliene, D.,Gewering, T.,Moeller, A. (deposition date: 2022-04-12, release date: 2023-04-26, Last modification date: 2024-03-20) |
| Primary citation | Gewering, T.,Waghray, D.,Parey, K.,Jung, H.,Tran, N.N.B.,Zapata, J.,Zhao, P.,Chen, H.,Januliene, D.,Hummer, G.,Urbatsch, I.,Moeller, A.,Zhang, Q. Tracing the substrate translocation mechanism in P-glycoprotein. Elife, 12:-, 2024 Cited by PubMed: 38259172DOI: 10.7554/eLife.90174 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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