7ZHP
Crystal structure of TTBK1 in complex with compound 9 (7-005)
Summary for 7ZHP
Entry DOI | 10.2210/pdb7zhp/pdb |
Descriptor | Tau-tubulin kinase 1, PHOSPHATE ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | kinase, ttbk1, tau tubulin kinase 1, inhibitor complex, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 36342.86 |
Authors | Chaikuad, A.,Axtman, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2022-04-06, release date: 2023-04-19, Last modification date: 2024-02-07) |
Primary citation | Bashore, F.M.,Marquez, A.B.,Chaikuad, A.,Howell, S.,Dunn, A.S.,Beltran, A.A.,Smith, J.L.,Drewry, D.H.,Beltran, A.S.,Axtman, A.D. Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis. Sci Rep, 13:6118-6118, 2023 Cited by PubMed: 37059819DOI: 10.1038/s41598-023-32854-4 PDB entries with the same primary citation |
Experimental method |
Structure validation
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