7ZGA

Structure of yeast Sec14p with ergoline

7ZGA の概要

• エントリーDOI: 10.2210/pdb7zga/pdb
• 分子名称: SEC14 cytosolic factor, ~{O}9-methyl ~{O}4-[2,2,2-tris(chloranyl)ethyl] (5~{a}~{S},6~{a}~{S},9~{R},10~{a}~{S})-7-methyl-3-nitro-5,5~{a},6,6~{a},8,9,10,10~{a}-octahydroindolo[4,3-fg]quinoline-4,9-dicarboxylate (3 entities in total)
• 機能のキーワード: sec14p, ergoline, lipid binding protein
• 由来する生物種: Saccharomyces cerevisiae S288C
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34524.33

構造登録者

Hong, Z.,Johnen, P.,Schaaf, G.,Bono, F. (登録日: 2022-04-03, 公開日: 2023-01-25, 最終更新日: 2024-02-07)

• 主引用文献: Chen, X.R.,Poudel, L.,Hong, Z.,Johnen, P.,Katti, S.,Tripathi, A.,Nile, A.H.,Green, S.M.,Khan, D.,Schaaf, G.,Bono, F.,Bankaitis, V.A.,Igumenova, T.I.; Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.; J.Biol.Chem., 299:102861-102861, 2023; PubMed: 36603766; DOI: 10.1016/j.jbc.2022.102861

実験手法

X-RAY DIFFRACTION (2.302 Å)