7ZET

Crystal structure of human Clusterin, crystal form I

Summary for 7ZET

Entry DOI	10.2210/pdb7zet/pdb
Descriptor	Clusterin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	molecular chaperone, complement system, alzheimer's disease, chaperone
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	48934.63
Authors	Yuste-Checa, P.,Bracher, A.,Hartl, F.U. (deposition date: 2022-03-31, release date: 2023-10-11, Last modification date: 2025-04-23)
Primary citation	Yuste-Checa, P.,Carvajal, A.I.,Mi, C.,Paatz, S.,Ulrich Hartl, F.,Bracher, A. Hydrophobic tails enable diverse functions of the extracellular chaperone clusterin Biorxiv, 2024 Cited by DOI: 10.1101/2024.10.30.620894 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation