7ZCH
CHMP2A-CHMP3 heterodimer (410 Angstrom diameter)
Summary for 7ZCH
Entry DOI | 10.2210/pdb7zch/pdb |
EMDB information | 14631 |
Descriptor | Charged multivesicular body protein 2a, Charged multivesicular body protein 3 (2 entities in total) |
Functional Keywords | cryo electron microscopy, helical reconstruction, membrane-bound chmp2a-chmp3 filament, negative-curvature membrane, cytosolic protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 35735.17 |
Authors | Azad, K.,Desfosses, A.,Effantin, G.,Schoehn, G.,Weissenhorn, W. (deposition date: 2022-03-28, release date: 2023-01-18, Last modification date: 2024-07-24) |
Primary citation | Azad, K.,Guilligay, D.,Boscheron, C.,Maity, S.,De Franceschi, N.,Sulbaran, G.,Effantin, G.,Wang, H.,Kleman, J.P.,Bassereau, P.,Schoehn, G.,Roos, W.H.,Desfosses, A.,Weissenhorn, W. Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage. Nat.Struct.Mol.Biol., 30:81-90, 2023 Cited by PubMed: 36604498DOI: 10.1038/s41594-022-00867-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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