7ZCE

SARS-CoV-2 Spike protein in complex with the single chain fragment scFv76

7ZCE の概要

• エントリーDOI: 10.2210/pdb7zce/pdb
• EMDBエントリー: 14628
• 分子名称: Spike glycoprotein,Fibritin, scFv76 single chain fragment, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, spike, single chain fragment, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 522470.58

構造登録者

Chaves-Sanjuan, A.,Bolognesi, M. (登録日: 2022-03-28, 公開日: 2022-10-12, 最終更新日: 2023-02-08)

• 主引用文献: Milazzo, F.M.,Chaves-Sanjuan, A.,Minenkova, O.,Santapaola, D.,Anastasi, A.M.,Battistuzzi, G.,Chiapparino, C.,Rosi, A.,Merlo Pich, E.,Albertoni, C.,Marra, E.,Luberto, L.,Viollet, C.,Spagnoli, L.G.,Riccio, A.,Rossi, A.,Santoro, M.G.,Ballabio, F.,Paissoni, C.,Camilloni, C.,Bolognesi, M.,De Santis, R.; Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery.; Mol.Ther., 31:362-373, 2022; PubMed: 36114671; DOI: 10.1016/j.ymthe.2022.09.010

実験手法

ELECTRON MICROSCOPY (3.5 Å)