7ZBN

Cryo-EM structure of the human GS-GN complex in the inhibited state

Summary for 7ZBN

• Entry DOI: 10.2210/pdb7zbn/pdb
• EMDB information: 14587
• Descriptor: Glycogen [starch] synthase, muscle, Isoform GN-1 of Glycogenin-1 (3 entities in total)
• Functional Keywords: glycosyltransferase, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 485579.06

Authors

Marr, L.,Zeqiraj, E. (deposition date: 2022-03-23, release date: 2022-06-22)

• Primary citation: Marr, L.,Biswas, D.,Daly, L.A.,Browning, C.,Vial, S.C.M.,Maskell, D.P.,Hudson, C.,Bertrand, J.A.,Pollard, J.,Ranson, N.A.,Khatter, H.,Eyers, C.E.,Sakamoto, K.,Zeqiraj, E.; Mechanism of glycogen synthase inactivation and interaction with glycogenin.; Nat Commun, 13:3372-3372, 2022; PubMed: 35690592; DOI: 10.1038/s41467-022-31109-6

Experimental method

ELECTRON MICROSCOPY (2.62 Å)