7ZB8
Crystal Structure of SARS-CoV-2 Main Protease (Mpro) variant K61A at 2.48 A resolution
Summary for 7ZB8
Entry DOI | 10.2210/pdb7zb8/pdb |
Descriptor | 3C-like proteinase nsp5, DIMETHYL SULFOXIDE (3 entities in total) |
Functional Keywords | sars-cov-2, mpro, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 2 |
Total formula weight | 67847.41 |
Authors | Paknia, E.,Rabe von Pappenheim, F.,Funk, L.-M.,Tittmann, K.,Chari, A. (deposition date: 2022-03-23, release date: 2022-06-01, Last modification date: 2024-01-31) |
Primary citation | Funk, L.M.,Poschmann, G.,Rabe von Pappenheim, F.,Chari, A.,Stegmann, K.M.,Dickmanns, A.,Wensien, M.,Eulig, N.,Paknia, E.,Heyne, G.,Penka, E.,Pearson, A.R.,Berndt, C.,Fritz, T.,Bazzi, S.,Uranga, J.,Mata, R.A.,Dobbelstein, M.,Hilgenfeld, R.,Curth, U.,Tittmann, K. Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design. Nat Commun, 15:411-411, 2024 Cited by PubMed: 38195625DOI: 10.1038/s41467-023-44621-0 PDB entries with the same primary citation |
Experimental method |
Structure validation
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