7Z9L
Phen-DC3 intercalation causes hybrid-to-antiparallel transformation of human telomeric DNA G-quadruplex
Summary for 7Z9L
Entry DOI | 10.2210/pdb7z9l/pdb |
NMR Information | BMRB: 34714 |
Descriptor | DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide (2 entities in total) |
Functional Keywords | g quadruplex, ligand intercalation, nmr spectroscopy, mass spectrometry, dna |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 7838.30 |
Authors | Ghosh, A.,Trajkovski, M.,Teulade-Fichou, M.P.,Gabelica, V.,Plavec, J. (deposition date: 2022-03-21, release date: 2022-08-31, Last modification date: 2024-05-15) |
Primary citation | Ghosh, A.,Trajkovski, M.,Teulade-Fichou, M.P.,Gabelica, V.,Plavec, J. Phen-DC 3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation. Angew.Chem.Int.Ed.Engl., 61:e202207384-e202207384, 2022 Cited by PubMed: 35993443DOI: 10.1002/anie.202207384 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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