7Z8Z

Crystal structure of the MEILB2-BRME1 2:2 core complex

Summary for 7Z8Z

Entry DOI	10.2210/pdb7z8z/pdb
Descriptor	Heat shock factor 2-binding protein, Break repair meiotic recombinase recruitment factor 1 (3 entities in total)
Functional Keywords	meiosis, dna repair, dna clamp, double-strand break, recombination
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	4
Total formula weight	23895.85
Authors	Gurusaran, M.,Davies, O.R. (deposition date: 2022-03-19, release date: 2023-09-20, Last modification date: 2024-08-14)
Primary citation	Gurusaran, M.,Zhang, J.,Zhang, K.,Shibuya, H.,Davies, O.R. MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination. Nat Commun, 15:6552-6552, 2024 Cited by PubMed: 39095423 DOI: 10.1038/s41467-024-50920-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation