7Z8U

Catalytic subunit HisG R56A mutant from Psychrobacter arcticus ATPPRT (HisGZ) in complex with ATP and PRPP

7Z8U の概要

• エントリーDOI: 10.2210/pdb7z8u/pdb
• 分子名称: ATP phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: atp, phosphoribosyltransferase, atpprt, prpp, hisg, hisgz, histidine, biosynthesis, allosteric, transferase
• 由来する生物種: Psychrobacter arcticus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26076.41

構造登録者

Alphey, M.S.,Fisher, G.,da Silva, R.G. (登録日: 2022-03-18, 公開日: 2022-03-30, 最終更新日: 2024-02-07)

• 主引用文献: Fisher, G.,Corbella, M.,Alphey, M.S.,Nicholson, J.,Read, B.J.,Kamerlin, S.C.L.,da Silva, R.G.; Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation.; Nat Commun, 13:7607-7607, 2022; PubMed: 36494361; DOI: 10.1038/s41467-022-34960-9

実験手法

X-RAY DIFFRACTION (2 Å)