7Z6R

Psychrobacter arcticus ATPPRT (HisGZ) R56A mutant bound to ATP and PRPP

Summary for 7Z6R

Entry DOI	10.2210/pdb7z6r/pdb
Descriptor	ATP phosphoribosyltransferase regulatory subunit, ATP phosphoribosyltransferase, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	phosphoribosyltransferase, atpprt, prpp, hisgz, histidine, biosynthesis, allosteric, transferase
Biological source	Psychrobacter arcticus More
Total number of polymer chains	4
Total formula weight	138362.28
Authors	Alphey, M.S.,Fisher, G.,da Silva, R.G. (deposition date: 2022-03-14, release date: 2022-03-23, Last modification date: 2024-02-07)
Primary citation	Fisher, G.,Corbella, M.,Alphey, M.S.,Nicholson, J.,Read, B.J.,Kamerlin, S.C.L.,da Silva, R.G. Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation. Nat Commun, 13:7607-7607, 2022 Cited by PubMed: 36494361 DOI: 10.1038/s41467-022-34960-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation