7Z5R
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035
Summary for 7Z5R
Entry DOI | 10.2210/pdb7z5r/pdb |
Descriptor | N-glycosylase/DNA lyase, (7~{R})-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)bicyclo[4.2.0]octa-1,3,5-triene-7-carboxamide, NICKEL (II) ION, ... (4 entities in total) |
Functional Keywords | ogg1, glycosylase, inhibitor, dna binding protein |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 3 |
Total formula weight | 108313.58 |
Authors | Davies, J.R.,Scaletti, E.,Stenmark, P. (deposition date: 2022-03-09, release date: 2023-03-22, Last modification date: 2024-02-07) |
Primary citation | Davies, J.R.,Scaletti, E.,Stenmark, P. Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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