7Z5N

Crystal structure of DYRK1A in complex with CX-4945

Summary for 7Z5N

• Entry DOI: 10.2210/pdb7z5n/pdb
• Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, SULFATE ION, ... (8 entities in total)
• Functional Keywords: kinase, diabetes, kinase inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 8
• Total formula weight: 353441.66

Authors

Pustelny, K.,Grygier, P.,Golik, P.,Dubin, G.,Czarna, A. (deposition date: 2022-03-09, release date: 2023-03-22, Last modification date: 2024-10-16)

• Primary citation: Grygier, P.,Pustelny, K.,Golik, P.,Popowicz, G.,Dubin, G.,Czarna, A.; Crystal structure DYRK1A in complex with CX-4945; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.77 Å)