7Z5C
Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit
Summary for 7Z5C
Entry DOI | 10.2210/pdb7z5c/pdb |
EMDB information | 14517 |
Descriptor | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... (4 entities in total) |
Functional Keywords | adaptor complex, ap2, trafficking, clathrin, ccp, protein transport |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 4 |
Total formula weight | 203374.82 |
Authors | Kane Dickson, V.,Qu, K.,Owen, D.J.,Briggs, J.A.,Zaccai, N.R. (deposition date: 2022-03-09, release date: 2022-05-11, Last modification date: 2024-07-17) |
Primary citation | Zaccai, N.R.,Kadlecova, Z.,Dickson, V.K.,Korobchevskaya, K.,Kamenicky, J.,Kovtun, O.,Umasankar, P.K.,Wrobel, A.G.,Kaufman, J.G.G.,Gray, S.R.,Qu, K.,Evans, P.R.,Fritzsche, M.,Sroubek, F.,Honing, S.,Briggs, J.A.G.,Kelly, B.T.,Owen, D.J.,Traub, L.M. FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8:eabn2018-eabn2018, 2022 Cited by PubMed: 35486718DOI: 10.1126/sciadv.abn2018 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.16 Å) |
Structure validation
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