7Z0X

THSC20.HVTR26 Fab bound to SARS-CoV-2 Receptor Binding Domain

7Z0X の概要

• エントリーDOI: 10.2210/pdb7z0x/pdb
• 分子名称: THSC20.HVTR26 Fab heavy chain, THSC20.HVTR26 Fab light chain, Spike protein S1, ... (6 entities in total)
• 機能のキーワード: neutralizing antibody, sars-cov-2, spike, rbd, antiviral protein, immunology
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 71557.85

構造登録者

Wibmer, C.K. (登録日: 2022-02-23, 公開日: 2022-04-13, 最終更新日: 2024-05-01)

• 主引用文献: Hingankar, N.,Deshpande, S.,Das, P.,Rizvi, Z.A.,Wibmer, C.K.,Mashilo, P.,Ansari, M.Y.,Burns, A.,Barman, S.,Zhao, F.,Mukherjee, S.,Torres, J.L.,Chattopadhyay, S.,Mehdi, F.,Sutar, J.,Rathore, D.K.,Pargai, K.,Singh, J.,Sonar, S.,Jakhar, K.,Dandotiya, J.,Bhattacharyya, S.,Mani, S.,Samal, S.,Singh, S.,Kshetrapal, P.,Thiruvengadam, R.,Batra, G.,Medigeshi, G.,Ward, A.B.,Bhatnagar, S.,Awasthi, A.,Sok, D.,Bhattacharya, J.; A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 Delta variant.; Plos Pathog., 18:e1010465-e1010465, 2022; PubMed: 35482816; DOI: 10.1371/journal.ppat.1010465

実験手法

X-RAY DIFFRACTION (1.8 Å)