7YXN

Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment

7YXN の概要

• エントリーDOI: 10.2210/pdb7yxn/pdb
• 分子名称: Ancestral Glucocorticoid Receptor2, SHP NR Box 1 Peptide, DEXAMETHASONE, ... (5 entities in total)
• 機能のキーワード: nuclear receptor, transcription factor, dexamethasone, nuclear protein
• 由来する生物種: unidentified; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 61048.95

構造登録者

Jimenez-Panizo, A.,Estebanez-Perpina, E.,Fuentes-Prior, P. (登録日: 2022-02-16, 公開日: 2022-12-07, 最終更新日: 2024-01-31)

• 主引用文献: Jimenez-Panizo, A.,Alegre-Marti, A.,Tettey, T.T.,Fettweis, G.,Abella, M.,Anton, R.,Johnson, T.A.,Kim, S.,Schiltz, R.L.,Nunez-Barrios, I.,Font-Diaz, J.,Caelles, C.,Valledor, A.F.,Perez, P.,Rojas, A.M.,Fernandez-Recio, J.,Presman, D.M.,Hager, G.L.,Fuentes-Prior, P.,Estebanez-Perpina, E.; The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.; Nucleic Acids Res., 50:13063-13082, 2022; PubMed: 36464162; DOI: 10.1093/nar/gkac1119

実験手法

X-RAY DIFFRACTION (2.46 Å)