7YXJ
Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2,4-PDCA
Summary for 7YXJ
Entry DOI | 10.2210/pdb7yxj/pdb |
Descriptor | GH14974p, MANGANESE (II) ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, jmjc, jmjc domain, jmjc domain-containing protein 7, jmjd7, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, hydroxylation, lysyl hydroxylation, dimerisation, translation factor, developmentally regulated gtp binding proteins, drg1, drg2, trafac gtpase, hypoxia, nucleic acid- binding, metal-binding, translation, helix-loop-helix-beta, dsbh, facial triad, development, cancer, ribosome biogenesis |
Biological source | Drosophila melanogaster (fruit fly) |
Total number of polymer chains | 4 |
Total formula weight | 148658.47 |
Authors | Chowdhury, R.,Schofield, C.J. (deposition date: 2022-02-16, release date: 2022-04-27, Last modification date: 2024-01-31) |
Primary citation | Chowdhury, R.,Abboud, M.I.,Wiley, J.,Tumber, A.,Markolovic, S.,Schofield, C.J. Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Sci Rep, 12:6065-6065, 2022 Cited by PubMed: 35410347DOI: 10.1038/s41598-022-10028-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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