7YTV

Crystal structure of Aspergillus fumigatus Thioredoxin reductase in complex with auranofin

7YTV の概要

• エントリーDOI: 10.2210/pdb7ytv/pdb
• 分子名称: Thioredoxin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: thioredoxin reductase, reductase, auranofin, oxidoreductase
• 由来する生物種: Aspergillus fumigatus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 82781.93

構造登録者

Lin, W. (登録日: 2022-08-16, 公開日: 2023-06-28, 最終更新日: 2023-11-29)

• 主引用文献: Chen, P.,Yang, J.,Jin, Y.,Lu, C.,Feng, Z.,Gao, F.,Chen, Y.,Wang, F.,Shang, Z.,Lin, W.; In vitro antifungal and antibiofilm activities of auranofin against itraconazole-resistant Aspergillus fumigatus.; J Mycol Med, 33:101381-101381, 2023; PubMed: 37037064; DOI: 10.1016/j.mycmed.2023.101381

実験手法

X-RAY DIFFRACTION (3.866 Å)