7YTN

Crystal structure of SARS-CoV-2 Alpha RBD in complex with the D27LEY neutralizing antibody Fab fragment

7YTN の概要

• エントリーDOI: 10.2210/pdb7ytn/pdb
• 分子名称: Heavy chain of Fab, Light chain of Fab, Spike protein S1 (3 entities in total)
• 機能のキーワード: antibody, antigen, complex, sars-cov-2, rbd, antiviral protein, antiviral protein-viral protein complex, antiviral protein/viral protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 80898.71

構造登録者

Jeong, B.S.,Jeon, J.Y.,Oh, B.H. (登録日: 2022-08-15, 公開日: 2023-06-28, 最終更新日: 2023-11-29)

• 主引用文献: Jeong, B.S.,Jeon, J.Y.,Lai, C.J.,Yun, H.Y.,Jung, J.U.,Oh, B.H.; Structural basis for the broad and potent cross-reactivity of an N501Y-centric antibody against sarbecoviruses.; Front Immunol, 13:1049867-1049867, 2022; PubMed: 36466915; DOI: 10.3389/fimmu.2022.1049867

実験手法

X-RAY DIFFRACTION (3.51 Å)