7YL2
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004
Summary for 7YL2
Entry DOI | 10.2210/pdb7yl2/pdb |
Descriptor | Bromodomain-containing protein 4, N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide, GLYCEROL, ... (5 entities in total) |
Functional Keywords | brd4(1), bromodomain, inhibitor, antitumor protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 17243.85 |
Authors | |
Primary citation | Huang, Y.,Wei, A.,Dong, R.,Xu, H.,Zhang, C.,Chen, Z.,Li, J.,Wu, X.,Zhang, Y.,Xu, Y. Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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