7YIU
Cryo-EM structure of the C6-ceramide-bound SPT-ORMDL3 complex
Summary for 7YIU
Entry DOI | 10.2210/pdb7yiu/pdb |
EMDB information | 33864 |
Descriptor | Serine palmitoyltransferase 2, Serine palmitoyltransferase 1, ORM1-like protein 3, ... (8 entities in total) |
Functional Keywords | ceramide, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 145181.64 |
Authors | |
Primary citation | Xie, T.,Liu, P.,Wu, X.,Dong, F.,Zhang, Z.,Yue, J.,Mahawar, U.,Farooq, F.,Vohra, H.,Fang, Q.,Liu, W.,Wattenberg, B.W.,Gong, X. Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14:3475-3475, 2023 Cited by PubMed: 37308477DOI: 10.1038/s41467-023-39274-y PDB entries with the same primary citation |
Experimental method |
Structure validation
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