7YIS

Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate

7YIS の概要

• エントリーDOI: 10.2210/pdb7yis/pdb
• 分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE (2 entities in total)
• 機能のキーワード: arap3, ph domain, complex, inositol 1, 3, 4, 5-tetrakisphosphate, cytosolic protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13773.29

構造登録者

Zhang, Y.J.,Liu, Y.R.,Wu, B. (登録日: 2022-07-18, 公開日: 2023-05-03, 最終更新日: 2023-11-29)

• 主引用文献: Zhang, Y.,Ge, L.,Xu, L.,Liu, Y.,Wang, J.,Liu, C.,Zhao, H.,Xing, L.,Wang, J.,Wu, B.; Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.; Int J Mol Sci, 24:-, 2023; PubMed: 36674645; DOI: 10.3390/ijms24021125

実験手法

X-RAY DIFFRACTION (3.3 Å)