7YHE

Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG

7YHE の概要

• エントリーDOI: 10.2210/pdb7yhe/pdb
• 分子名称: CmnC, 2-OXOGLUTARIC ACID, TRIETHYLENE GLYCOL, ... (5 entities in total)
• 機能のキーワード: hydroxylase, oxygenase, oxidoreductase
• 由来する生物種: Saccharothrix mutabilis subsp. capreolus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 78739.34

構造登録者

Huang, S.J.,Hsiao, Y.H.,Lin, E.C.,Hsiao, P.Y.,Chang, C.Y. (登録日: 2022-07-13, 公開日: 2023-07-19, 最終更新日: 2023-11-29)

• 主引用文献: Hsiao, Y.H.,Huang, S.J.,Lin, E.C.,Hsiao, P.Y.,Toh, S.I.,Chen, I.H.,Xu, Z.,Lin, Y.P.,Liu, H.J.,Chang, C.Y.; Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.; Front Chem, 10:1001311-1001311, 2022; PubMed: 36176888; DOI: 10.3389/fchem.2022.1001311

実験手法

X-RAY DIFFRACTION (1.67 Å)