7YFY

Cryo-EM structure of the Mili-piRNA- target ternary complex

Summary for 7YFY

• Entry DOI: 10.2210/pdb7yfy/pdb
• EMDB information: 33801
• Descriptor: Piwi-like protein 2, RNA (5'-R(P*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), piRNA, ... (4 entities in total)
• Functional Keywords: pirna, piwi protein, argonaute, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 104955.67

Authors

Li, Z.Q.,Liu, H.B.,Wu, J.P.,Shen, E.Z. (deposition date: 2022-07-09, release date: 2024-01-24, Last modification date: 2024-05-08)

• Primary citation: Li, Z.,Li, Z.,Zhang, Y.,Zhou, L.,Xu, Q.,Li, L.,Zeng, L.,Xue, J.,Niu, H.,Zhong, J.,Yu, Q.,Li, D.,Gui, M.,Huang, Y.,Tu, S.,Zhang, Z.,Song, C.Q.,Wu, J.,Shen, E.Z.; Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.; Nat.Struct.Mol.Biol., 2024; PubMed: 38658622; DOI: 10.1038/s41594-024-01287-6

Experimental method

ELECTRON MICROSCOPY (3.4 Å)