7YFQ

Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex

Summary for 7YFQ

• Entry DOI: 10.2210/pdb7yfq/pdb
• EMDB information: 33797
• Descriptor: piRNA, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), Piwi, ... (4 entities in total)
• Functional Keywords: pirna, piwi protein, argonaute, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Ephydatia fluviatilis; More
• Total number of polymer chains: 3
• Total formula weight: 105760.54

Authors

Li, Z.Q.,Liu, H.B.,Wu, J.P.,Shen, E.Z. (deposition date: 2022-07-08, release date: 2024-02-14, Last modification date: 2024-05-08)

• Primary citation: Li, Z.,Li, Z.,Zhang, Y.,Zhou, L.,Xu, Q.,Li, L.,Zeng, L.,Xue, J.,Niu, H.,Zhong, J.,Yu, Q.,Li, D.,Gui, M.,Huang, Y.,Tu, S.,Zhang, Z.,Song, C.Q.,Wu, J.,Shen, E.Z.; Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.; Nat.Struct.Mol.Biol., 2024; PubMed: 38658622; DOI: 10.1038/s41594-024-01287-6

Experimental method

ELECTRON MICROSCOPY (3.2 Å)