7YFD

Cryo-EM structure of the imetit-bound histamine H4 receptor and Gq complex

Summary for 7YFD

• Entry DOI: 10.2210/pdb7yfd/pdb
• EMDB information: 33786
• Descriptor: Engineered G-alpha-q, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, ... (8 entities in total)
• Functional Keywords: gpcr, aminergic receptor, histamine receptor, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 196750.47

Authors

Im, D.,Iwata, S.,Asada, H. (deposition date: 2022-07-08, release date: 2023-10-25, Last modification date: 2024-05-08)

• Primary citation: Im, D.,Kishikawa, J.I.,Shiimura, Y.,Hisano, H.,Ito, A.,Fujita-Fujiharu, Y.,Sugita, Y.,Noda, T.,Kato, T.,Asada, H.,Iwata, S.; Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor.; Nat Commun, 14:6538-6538, 2023; PubMed: 37863901; DOI: 10.1038/s41467-023-42260-z

Experimental method

ELECTRON MICROSCOPY (3.1 Å)